منابع مشابه
Thrombophilia in East Asian countries: are there any genetic differences in these countries?
In recent years, genetic analyses of congenital deficiencies of three anticoagulant proteins, antithrombin, protein C (PC) and protein S (PS), in East Asian patients with venous thromboembolism (VTE) have greatly increased. The PS-K196E mutation is often identified in the Japanese population with an allelic frequency of 0.86 %, and a total of approximately 10,000 Japanese are estimated to be ho...
متن کاملHereditary thrombophilia
Thrombophilia can be defined as a predisposition to form clots inappropriately. Thrombotic events during infancy and childhood are increasingly recognized as a significant source of mortality and morbidity. The predisposition to form clots can arise from genetic factors, acquired changes in the clotting mechanism, or, more commonly, an interaction between genetic and acquired factors. Since the...
متن کاملThrombophilia Screening.
Although controversial, screening for thrombophilia has become common. Testing for antiphospholipid antibodies is indicated in order to guide treatment decisions if there is clinical suspicion for antiphospholipid syndrome. The utility of identifying other thrombophilias in symptomatic venous thromboembolism (VTE) is questionable, as the risk of recurrence does not appear to be increased by an ...
متن کاملThrombophilia and pulmonary endarterectomy.
UNLABELLED In the present study, we compared groups of patients with and without thrombophilia, who underwent pulmonary endarterectomy (PEA), definitive treatment for chronic pulmonary hypertension resulting from thromboembolic disease. METHODS AND PATIENTS Between September 2004 and June 2007, we operated 54 patients with CTEPH. We divided our patients into three groups. Group I patients, ha...
متن کاملInherited thrombophilia: Part 2.
From the 'Charing Cross and Westminster Medical School, London, UK; 1RCCS Maggiore Hospital, Milan, Italy; Beth Israel Hospital, Boston USA; Universitv Hospital Leiden, The Netherlands; Research Centre of Medical Genetics, Moscow, The Russian Federation; WHO, Switzerland; Christian Medical College Hospital, Vellore, India; University of Lund, Malmö, Sweden; 'Institute of Clinical Genetics, Mosc...
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ژورنال
عنوان ژورنال: Japanese Journal of Thrombosis and Hemostasis
سال: 2012
ISSN: 0915-7441,1880-8808
DOI: 10.2491/jjsth.23.379